The Skins Frames Icons Debuffs General tab allows for various icon settings, including the position of the icons, scale of the icons and independent opacity to the bar
Icon position - Set the position of icons relative to the bar
On bar - Position icons on the bar
Off bar - Position icons on the side of the bar
Below bar - Position icons below the bar
Icon anchor - Set the location of the icon based on the icon position and relative to the health bar
Vertical offset - Offset the icon relative to the anchor
Horizontal offset - Offset the icon relative to the anchor
Max icons - Set the maximum number of debuff icons that can be shown at any one time
Icon scale - The icon scale relative to the bar
Icon spacer - Set the space between debuff icons
Double row - Stack 2 icons in each column, NOTE: Each icon scale is halved when using Double row.
Opacity: Always use enabled - Always use enabled bar opacity setting even when the bar is using a different setting
Opacity: Fade on expire - Fade the icon as it begins to expire
Fade start time - Set when the fade begins, normally set this 3 or 4 seconds higher than when you want to fade effect to be visible